原创力文档Chronic alcohol ingestion exacerbates skeletal muscle myopathy in HIV-1 transgenic rats.docVIP
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Chronic alcohol ingestion exacerbates skeletal muscle myopathy in HIV-1 transgenic rats
Claryetal.AIDSResearchandTherapy2011,8:30
/content/8/1/30
RESEARCH
OpenAccess
Chronicalcoholingestionexacerbatesskeletal
musclemyopathyinHIV-1transgenicrats
CarolineRClary*,DanielMGuidot*,MargauxABratinaandJeffreySOtis
Abstract
Background:Separately,chronicalcoholingestionandHIV-1infectionareassociatedwithsevereskeletalmuscle
derangements,includingatrophyandwasting,weakness,andfatigue.Oneprospectivecohortstudyreportedthat
41%ofHIV-infectedpatientsmetthecriteriaforalcoholism,however;fewreportsexistontheco-morbideffectsof
thesetwodiseaseprocessesonskeletalmusclehomeostasis.Thus,weanalyzedtheat
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