Classification of human genomic regions based on experimentally determined binding sites of more than 100 transcription-related factors.docVIP

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Classification of human genomic regions based on experimentally determined binding sites of more than 100 transcription-related factors.doc

Classification of human genomic regions based on experimentally determined binding sites of more than 100 transcription-related factors

Yipetal.GenomeBiology2012,13:R48 /2012/13/9/R48 RESEARCH OpenAccess Classificationofhumangenomicregionsbased onexperimentallydeterminedbindingsitesof morethan100transcription-relatedfactors KevinYYip1,2,3,4,5,ChaoCheng1,2,NitinBhardwaj1,2,JamesBBrown6,JingLeng1,AnshulKundaje7, JoelRozowsky1,2,EwanBirney8,PeterBickel6,MichaelSnyder9andMarkGerstein1,2,10* Abstract Background:Transcriptionfactorsfunctionbybindingdifferentclassesofregulatoryelements.TheEncyclopedia ofDNAElements(ENCODE)projecthasrecentlyproducedbindingdataformorethan100transcriptionfactors fromabout500ChIP-seqexperimentsinmultiple

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