Clinical and serological evaluation of a novel CENP-A peptide based ELISA.docVIP

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Clinical and serological evaluation of a novel CENP-A peptide based ELISA.doc

Clinical and serological evaluation of a novel CENP-A peptide based ELISA

Mahler et al. Arthritis Research Therapy 2010, 12:R99 /content/12/3/R99 RESEARCH ARTICLE Open Access Clinical and serological evaluation of a novel Research article CENP-A peptide based ELISA Michael Mahler1,2, Liesbeth Maes3, Daniel Blockmans3, Rene Westhovens3, Xavier Bossuyt3, Gabriela Riemekasten4, Sandra Schneider4, Falk Hiepe4, Andreas Swart5, Irmgard Gürtler5, Karl Egerer6, Margrit Fooke1,2 and Marvin J Fritzler*7 Abstract Introduction: Anti-centromere antibodies (ACA) are useful biomarkers in the diagnosis of systemic sclerosis (SSc). ACA are found in 20 to 40% of SSc patients

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