Clinical review Blood purification for sepsis.docVIP

Rimmelé and Kellum Critical Care 2011,15:205 /content/15/1/205 RE VIE W Clinical review: Blood puri? cation for sepsis Thomas Rimmelé and John A Kellum* sepsis or develop it during their intensive care unit stay. Abstract Hospital mortality rates are 27%, reaching 54% in the case of septic shock [2]. Sepsis is the primary cause of death in the intensive care unit. Extracorporeal blood puri?cation therapies have been proposed for patients with sepsis in order to improve outcomes since these therapies can alter the host in?ammatory response by non-selective removal of in?ammatory me