Combined treatment with dexamethasone and raloxifene totally abrogates osteoporosis and joint destruction in experimental postmenopausal arthritis.docVIP

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Combined treatment with dexamethasone and raloxifene totally abrogates osteoporosis and joint destruction in experimental postmenopausal arthritis.doc

Combined treatment with dexamethasone and raloxifene totally abrogates osteoporosis and joint destruction in experimental postmenopausal arthritis

Islanderetal.ArthritisResearchTherapy2011,13:R96 /content/13/3/R96 RESEARCH ARTICLE OpenAccess Combinedtreatmentwithdexamethasoneand raloxifenetotallyabrogatesosteoporosisand jointdestructioninexperimentalpostmenopausal arthritis UlrikaIslander*?,CarolineJochems?,AlexandraStubelius,AnnicaAndersson,MarieKLagerquist,ClaesOhlssonand HansCarlsten Abstract Introduction:Postmenopausalpatientswithrheumatoidarthritis(RA)areoftentreatedwithcorticosteroids.Lossof estrogen,theinflammatorydiseaseandexposuretocorticosteroidsallcontributetothedevelopmentof osteoporosis.Therefore,ouraimwastoinvestigateifa

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Combined treatment with dexamethasone and raloxifene totally abrogates osteoporosis and joint destruction in experimental postmenopausal arthritis.docVIP