原创力文档Comparative transcriptomic profile analysis of fed-batch cultures expressing different recombinant proteins in Escherichia coli.docVIP
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Comparative transcriptomic profile analysis of fed-batch cultures expressing different recombinant proteins in Escherichia coli
Sharmaetal.AMBExpress2011,1:33
/content/1/1/33
ORIGINAL
OpenAccess
Comparativetranscriptomicprofileanalysisof
fed-batchculturesexpressingdifferent
recombinantproteinsinEscherichiacoli
AshishKSharma,ShubhashreeMahalik,ChaitaliGhosh,AnuradhaBSinghandKrishnaJMukherjee*
Abstract
Thereisaneedtoelucidatetheproductspecificfeaturesofthemetabolicstressresponseofthehostcelltothe
inductionofrecombinantproteinsynthesis.Forthis,themethodofchoiceistranscriptomicprofilingwhich
providesabetterinsightintothechangestakingplaceincomplexglobalmetabolicnetworks.Thetranscriptomic
profilesofthreefed-batchculturese
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