Computer-aided diagnosis of renal obstruction utility of log-linear modeling versus standard ROC and kappa analysis.docVIP

Manatungaetal.EJNMMIResearch2011,1:5 /content/1/1/5 ORIGINAL RESEARCH OpenAccess Computer-aideddiagnosisofrenalobstruction: utilityoflog-linearmodelingversusstandardROC andkappaanalysis AmitaKManatunga1,JoséNiloGBinongo1andAndrewTTaylor2* Abstract Background:Theaccuracyofcomputer-aideddiagnosis(CAD)softwareisbestevaluatedbycomparisontoagold standardwhichrepresentsthetruestatusofdisease.Inmanysettings,however,knowledgeofthetruestatusof diseaseisnotpossibleandaccuracyisevaluatedagainsttheinterpretationsofanexpertpanel.Commonstatistical approachestoevaluateaccuracyincludereceiveroperatingchara