Control of endogenous gene expression timing by introns.docVIP

Oswald and Oates Genome Biology 2011,12:107 /2011/12/3/107 RESEARCH HIGHLIGHT Control of endogenous gene expression timing by introns Annelie Oswald and Andrew C Oates* Presence of introns in reporter genes alters timing Abstract of protein expression Comparison of gene expression from transgenes and endogenous genes with or without introns reveals a time-regulating role of introns in natural biological systems. To test whether intron-related time delays could a?ect gene expression, Takashima et al. [7] generated intron- containing (In(+)) and intron-less (In