Duration of red blood cell storage is associated with increased incidence of deep vein thrombosis and in hospital mortality in patients with traumatic injuries.docVIP

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Duration of red blood cell storage is associated with increased incidence of deep vein thrombosis and in hospital mortality in patients with traumatic injuries.doc

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Duration of red blood cell storage is associated with increased incidence of deep vein thrombosis and in hospital mortality in patients with traumatic injuries

Available online /content/13/5/R151 Research Open Access Vol 13 No 5 Duration of red blood cell storage is associated with increased incidence of deep vein thrombosis and in hospital mortality in patients with traumatic injuries Philip C Spinella1,2, Christopher L Carroll1, Ilene Staff3, Ronald Gross4, Jacqueline Mc Quay4, Lauren Keibel1, Charles E Wade2 and John B Holcomb5 1Department of Pediatrics, Connecticut Childrens Medical Center, 282 Washington Street, Hartford, CT 06106, USA 2Department of Combat Casualty Care Research, United States Army Institute of Surgical Research, 3400 Rawley E. Chambers Avenue, Fort Sam Houston, TX 78234, USA 3Department of Research, Hartford Hospital, 80 Seymour Street, Hartford, CT 06102-5037, USA 4Department of Surgery and Emergency Medicine, Hartford Hospital, 80 Seymour Street, Hartford, CT 06102-5037, USA 5Department of Acute Care Surgery, University of Texas Health Science Center, 6410 Fanin St, Houston, TX 77030, USA Corresponding author: Philip C Spinella, phil_spinella@ Received: 12 Jun 2009 Revisions requested: 31 Jul 2009 Revisions received: 6 Aug 2009 Accepted: 22 Sep 2009 Published: 22 Sep 2009 Critical Care 2009, 13:R151 (doi:10.1186/cc8050) This article is online at: /content/13/5/R151 ? 2009 Spinella et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction In critically ill patients the relationship between the storage age of red blood cells (RBCs) transfused and outcomes are controversial. To determine if duration of RBC storage is associated with adverse outcomes we studied critically ill trauma patients requiring transfusion. differences in admission vital signs, laboratory values, use of DVT prophylaxis, blood products or Injury Severity