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Echocardiographic assessment of pulmonary artery occlusion pressure in ventilated patients a transoesophageal study.doc

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Echocardiographic assessment of pulmonary artery occlusion pressure in ventilated patients a transoesophageal study

Available online /content/12/1/R18 Research Open Access Vol 12 No 1 Echocardiographic assessment of pulmonary artery occlusion pressure in ventilated patients: a transoesophageal study Philippe Vignon1,2,3, Ali AitHssain4, Bruno Fran?ois1,2, Pierre-Marie Preux3,5, Nicolas Pichon1,2, Marc Clavel1,2, Jean-Pierre Frat6 and Hervé Gastinne1,3 1Medical-surgical Intensive Care Unit, Dupuytren Teaching Hospital, 2 Ave. Martin Luther King, 87000 Limoges, France 2Centre dInvestigation Clinique, Dupuytren Teaching Hospital, 2 Ave. Martin Luther King, 87000 Limoges, France 3University of Limoges, Department of Medicine, 2 Rue du Dr Marcland, 87000 Limoges, France 4Medical Intensive Care Unit, Teaching Hospital, Rue Montalembert, BP 69, 63000 Clermont-Ferrand, France 5Unit of Clinical Research and Biostatistics, Dupuytren Teaching Hospital, 2 Ave. Martin Luther King, 87000 Limoges, France 6Medical Intensive Care Unit, Jean Bernard Teaching Hospital, Rue de la Miletrie, 86000 Poitiers, France Corresponding author: Philippe Vignon, philippe.vignon@unilim.fr Received: 31 Aug 2007 Revisions requested: 14 Oct 2007 Revisions received: 18 Dec 2007 Accepted: 19 Feb 2008 Published: 19 Feb 2008 Critical Care 2008, 12:R18 (doi:10.1186/cc6792) This article is online at: /content/12/1/R18 ? 2008 Vignon et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background Non-invasive evaluation of left ventricular filling Results In protocol A, Doppler parameters had similar area under the receiver operating characteristic (ROC) curve. In protocol B, mitral E/A ≤ 1.4, pulmonary vein S/D 0.65 and systolic fraction 44% best predicted an invasive PAOP ≤ 18 mmHg. Lateral E/E ≤ 8.0 or E/Vp ≤ 1.7 predicted a PAOP ≤ 18 mmHg with a