Esophageal capnometry during hemorrhagic shock and after resuscitation in rats.docVIP

Available online /content/7/1/79 Open Access Research Esophageal capnometry during hemorrhagic shock and after resuscitation in rats Balagangadhar R Totapally1, Harun Fakioglu2, Dan Torbati3 and Jack Wolfsdorf4 1Intensivist, Division of Critical Care Medicine, Miami Children’s Hospital, Miami, Florida, USA 2Fellow Pediatric Care Medicine, Division of Critical Care Medicine, Miami Children’s Hospital, Miami, Florida, USA 3Associate Professor and Research Director, Division of Critical Care Medicine, Miami Children’s Hospital, Miami, Florida, USA 4Clinical Professor of Pediatric and Director, Division of Critical Care Medicine, Miami Children’s Hospital, Miami, Florida, USA Correspondence: Dan Torbati, Dan.Torbati@MCH.Com Received: 14 August 2002 Critical Care 2003, 7:79-84 (DOI 10.1186/cc1856) This article is online at /content/7/1/79 Revisions requested: 15 October 2002 Revisions received: 7 November 2002 Accepted: 8 November 2002 ? 2003 Totapally et al., licensee BioMed Central Ltd (Print ISSN 1364-8535; Online ISSN 1466-609X). This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any non-commercial purpose, provided this notice is preserved along with the articles original URL. Published: 20 December 2002 Abstract Background Splanchnic perfusion following hypovolemic shock is an important marker of adequate resuscitation. We tested whether the gap between esophageal partial carbon dioxide tension (PeCO ) 2 and arterial partial carbon dioxide tension (PaCO ) is increased during graded hemorrhagic 2 hypotension and reversed after blood reinfusion, using a fiberoptic carbon dioxide sensor. Materials and method Ten Sprague–Dawley rats were anesthetized, tracheotomized, and cannulated in one femoral artery and vein. A calibrated fiberoptic PCO probe was inserted into the distal third of 2 the esophagus for determination of luminal PeCO during maintained anesthesia