Expert agreement confirms that negative changes in hand and foot radiographs are a surrogate for repair in patients with rheumatoid arthritis.docVIP

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Expert agreement confirms that negative changes in hand and foot radiographs are a surrogate for repair in patients with rheumatoid arthritis.doc

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Available online /content/9/4/R62 Research article Open Access Vol 9 No 4 Expert agreement confirms that negative changes in hand and foot radiographs are a surrogate for repair in patients with rheumatoid arthritis Désirée van der Heijde1, Robert Landewé2, Annelies Boonen2, Steve Einstein3, Gertraud Herborn4, Rolf Rau4, Siegfried Wassenberg4, Barbara N Weissman5, Carl S Winalski6 and John T Sharp7 1Department of Rheumatology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, The Netherlands 2Department of Rheumatology, University Hospital Maastricht, and CAPHRI Research Institute, PO Box 5800, Maastricht 6202 AZ, The Netherlands 3BioImaging Technologies, 826 Newtown-Yardley Road, Newtown, PA 18940, USA 4Department of Rheumatology, Evangelisches Fachkrankenhaus Ratingen, Rosenstrasse 2, Ratingen D-40882, Germany 5Department of Radiology, Brigham Womens Hospital, 75 Francis Street, Boston, MA 02115, USA 6Department of Radiology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA 7Department of Rheumatology, University of Washington, 8387 NE Sunamee Place, Bainbridge Island, WA 98110, USA Corresponding author: Désirée van der Heijde, d.vanderheijde@kpnplanet.nl Received: 17 May 2006 Revisions requested: 6 Jul 2006 Revisions received: 25 Apr 2007 Accepted: 2 Jul 2007 Published: 2 Jul 2007 Arthritis Research Therapy 2007, 9:R62 (doi:10.1186/ar2220) This article is online at: /content/9/4/R62 ? 2007 van der Heijde et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract The objective of the present study was to test the hypothesis that experts recognize repair of erosions and, if so, to determine which, if any, morphologic features permitted them to recognize the repair. We also t