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Exploiting Nonlinear Recurrence and Fractal Scaling Properties for Voice Disorder Detection.doc

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Exploiting Nonlinear Recurrence and Fractal Scaling Properties for Voice Disorder Detection

BioMedical Engineering OnLine BioMedCentral Research Open Access Exploiting Nonlinear Recurrence and Fractal Scaling Properties for Voice Disorder Detection Max A Little*1,2,3, Patrick E McSharry1, Stephen J Roberts2, Declan AE Costello4 and Irene M Moroz3 Address: 1Systems Analysis, Modelling and Prediction Group, Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, UK, 2Pattern Analysis Research Group, Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, UK, 3Applied Dynamical Systems Research Group, Oxford Centre for Industrial and Applied Mathematics, Mathematics Institute, University of Oxford, Oxford OX1 3JP, UK and 4Milton Keynes General Hospital, Standing Way, Eaglestone, Milton Keynes, Bucks MK6 5LD, UK Email: Max A Little* - littlem@robots.ox.ac.uk; Patrick E McSharry - mcsharry@robots.ox.ac.uk; Stephen J Roberts - sjrob@robots.ox.ac.uk; Declan AE Costello - declancostello@.uk; Irene M Moroz - moroz@maths.ox.ac.uk * Corresponding author Published: 2 6 June 2 007 Received: 6 March 2 007 Accepted: 2 6 June 2 007 BioMedical Engineering OnLine 2 007, 6:2 3 doi:10.1186/1475-92 5X-6-2 3 This article is available from: /content/6/1/2 3 ? 2 007 Little et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2 .0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Voice disorders affect patients profoundly, and acoustic tools can potentially measure voice function objectively. Disordered sustained vowels exhibit wide-ranging phenomena, from nearly periodic to highly complex, aperiodic vibrations, and increased breathiness. Modelling and surrogate data studies have shown significant nonlinear and non-Gaussian random properties in these sounds. Nonetheless, existing tools