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Exploratory analysis of obsessive compulsive symptom dimensions in children and adolescents a Prospective follow-up study.doc

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Exploratory analysis of obsessive compulsive symptom dimensions in children and adolescents a Prospective follow-up study

BMC Psychiatry BioMedCentral Research article Open Access Exploratory analysis of obsessive compulsive symptom dimensions in children and adolescents: a Prospective follow-up study Richard Delorme*1,2, Arnaud Bille3, Catalina Betancur1, Flavie Mathieu1, Nadia Chabane1,2, Marie Christine Mouren-Simeoni2 and Marion Leboyer1,3 Address: 1INSERM U513, Faculté de Médecine, Université Paris XII, Créteil, France, 2Service de Psychopathologie de lEnfant et de lAdolescent, H?pital Robert Debré, Assistance Publique-H?pitaux de Paris, Paris, France and 3Service de Psychiatrie, H?pital Henri Mondor et Albert Chenevier, Assistance Publique-H?pitaux de Paris, Créteil, France Email: Richard Delorme* - delorme@im3.inserm.fr; Arnaud Bille - arnaud.bille@tiscali.fr; Catalina Betancur - betancur@im3.inserm.fr; Flavie Mathieu - mathieu@im3.inserm.fr; Nadia Chabane - chabane@im3.inserm.fr; Marie Christine Mouren- Simeoni - marie_christine.mouren_simeoni@rdb.ap-hop-paris.fr; Marion Leboyer - leboyer@im3.inserm.fr * Corresponding author Published: 05 January 2006 Received: 13 June 2005 Accepted: 05 January 2006 BMC Psychiatry 2006, 6:1 doi:10.1186/1471-244X-6-1 This article is available from: /1471-244X/6/1 ? 2006 Delorme et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Recent statistical approaches based on factor analysis of obsessive compulsive (OC) symptoms in adult patients have identified dimensions that seem more effective in symptom-based taxonomies and appear to be more stable over time. Although a phenotypic continuum from childhood to adulthood has been hypothesized, no factor analytic studies have been performed in juvenile patients, and the stability of OC dimensions in children and adoles