Exploring transcriptional signalling mediated by OsWRKY13, a potential regulator of multiple physiological processes in rice.docVIP

Exploring transcriptional signalling mediated by OsWRKY13, a potential regulator of multiple physiological processes in rice.doc

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Exploring transcriptional signalling mediated by OsWRKY13, a potential regulator of multiple physiological processes in rice

BMC Plant Biology BioMedCentral Research article Open Access Exploring transcriptional signalling mediated by OsWRKY13, a potential regulator of multiple physiological processes in rice Deyun Qiu?, Jun Xiao?, Weibo Xie, Hongtao Cheng, Xianghua Li and Shiping Wang* Address: National Key Laboratory of Crop Genetic Improvement, National Center of Plant Gene Research (Wuhan), Huazhong Agricultural University, Wuhan 430070, PR China Email: Deyun Qiu - qiudeyun@; Jun Xiao - shawn@; Weibo Xie - xwbcn@; Hongtao Cheng - chenghongtao@; Xianghua Li - xhli@; Shiping Wang* - swang@ * Corresponding author ?Equal contributors Published: 18 June 2009 Received: 22 October 2008 Accepted: 18 June 2009 BMC Plant Biology 2009, 9:74 doi:10.1186/1471-2229-9-74 This article is available from: /1471-2229/9/74 ? 2009 Qiu et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Rice transcription regulator OsWRKY13 influences the functioning of more than 500 genes in multiple signalling pathways, with roles in disease resistance, redox homeostasis, abiotic stress responses, and development. Results: To determine the putative transcriptional regulation mechanism of OsWRKY13, the putative cis-acting elements of OsWRKY13-influenced genes were analyzed using the whole genome expression profiling of OsWRKY13-activated plants generated with the Affymetrix GeneChip Rice Genome Array. At least 39 transcription factor genes were influenced by OsWRKY13, and 30 of them were downregulated. The promoters of OsWRKY13-upregulated genes were overrepresented with W-boxes for WRKY protein binding, whereas the promoters of OsWRKY13-downregulated genes were enriched with cis-elements

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