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Factors determining the outcome of children hospitalized with severe pneumonia.doc

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Factors determining the outcome of children hospitalized with severe pneumonia

BMC Pediatrics BioMedCentral Research article Open Access Factors determining the outcome of children hospitalized with severe pneumonia Karalanglin Tiewsoh1, Rakesh Lodha1, Ravindra M Pandey2, Shobha Broor3, M Kalaivani2 and Sushil K Kabra*1 Address: 1Department of Pediatrics, All India Institute of Medical Sciences, New Delhi 110029, India, 2Department of Biostatistics, All India Institute of Medical Sciences, New Delhi 110029, India and 3Department of Microbiology, All India Institute of Medical Sciences, New Delhi 110029, India Email: Karalanglin Tiewsoh - karalanglin@; Rakesh Lodha - rakesh_lodha@; Ravindra M Pandey - rmpandey@; Shobha Broor - shobha.broor@; M Kalaivani - manikalaivani@yahoo.co.in; Sushil K Kabra* - skkabra@ * Corresponding author Published: 23 February 2009 Received: 5 August 2008 Accepted: 23 February 2009 BMC Pediatrics 2009, 9:15 doi:10.1186/1471-2431-9-15 This article is available from: /1471-2431/9/15 ? 2009 Tiewsoh et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Pneumonia is one of the leading causes of morbidity and mortality in under fives. We carried out a comprehensive study to identify factors influencing both mortality and morbidity for children less than 5 years of age hospitalized with severe pneumonia. Methods: 200 hospitalized children aged 2–60 months with World Health Organization (WHO) defined severe pneumonia were enrolled in the study. The children were managed using a standard protocol. They were closely followed up for need for change in antibiotics, prolonged hospital stay, need for mechanical ventilation and mortality. Data on the factors influencing the outcome were collected. Results: Of 200 children enrolled in the study, 113