Fatal necrotizing pneumonia due to a Panton-Valentine leukocidin positive community-associated methicillin-sensitive Staphylococcus aureus and Influenza co-infection a case report.docVIP

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Fatal necrotizing pneumonia due to a Panton-Valentine leukocidin positive community-associated methicillin-sensitive Staphylococcus aureus and Influenza co-infection a case report.doc

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Fatal necrotizing pneumonia due to a Panton-Valentine leukocidin positive community-associated methicillin-sensitive Staphylococcus aureus and Influenza co-infection a case report

Annals of Clinical Microbiology and Antimicrobials BioMedCentral Case report Open Access Fatal necrotizing pneumonia due to a Panton-Valentine leukocidin positive community-associated methicillin-sensitive Staphylococcus aureus and Influenza co-infection: a case report Jill C Roberts*1, Sam P Gulino2, K Kealy Peak1, Vicki A Luna1 and Roger Sanderson3 Address: 1Center for Biological Defense, College of Public Health, University of South Florida, Tampa Florida, USA, 2College of Medicine, University of South Florida and Hillsborough County Medical Examiner Department, Tampa Florida, USA and 3Bureau of Laboratories – Tampa, Florida Department of Health, Tampa, Florida, USA Email: Jill C Roberts* - jroberts@; Sam P Gulino - gulinos@; K Kealy Peak - kpeak1@; Vicki A Luna - vluna@; Roger Sanderson - Roger_Sanderson@doh.state.fl.us * Corresponding author Published: 19 February 2008 Received: 3 December 2007 Accepted: 19 February 2008 Annals of Clinical Microbiology and Antimicrobials 2008, 7:5 doi:10.1186/1476-0711-7-5 This article is available from: /content/7/1/5 ? 2008 Roberts et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Recent studies have described a number of fatalities due to methicillin-resistant Staphylococcus aureus (MRSA) and influenza virus co-infection. MRSA isolates provide a challenge to caregivers due to inherent wide range antibiotic resistance. Many facilities have instituted screening methods, based on the presence of antibiotic resistance genes, to identify MRSA positive patients upon admission. However, the resistance profile of the pathogen does not necessarily determine the severity of disease caused by that organism. We describe a fatal case of necrotizi