血清 GGT、ALT 对 2 型糖尿病早期诊断价值的初步探讨.pdfVIP

检验医学2010 笠主且第铅笔§第5 期 Lahoratory Medicine , M的 2010 ， Vo125. No 5. .349. 文章编号:167308例。(20IO)05.{)349-03 中团分类号:Q555 文献标识码:A 血清 GGT， ALT 对2 型糖尿病早期诊断价值的初步探讨 中春梅， 正龙武， 五妹芳 (复旦大学附膊上海市第五人民医院检验科，上海 2(0240) 摘要:目的 探讨血清γ，谷氨酸基转移酶(GGT) 、两氨酸氨基转移酶(ALT) 对2 型糖尿躏早期诊断的临床 应用价值。方法 采用 Roche Modular 全自动生化分析仪及配套试剂检测2∞例2 型糖尿病患者(男、女各 lω 例)及2∞名正常对照者的血清葡萄糖(Glu) 、 GGT 和 ALT 水平，并进行统计分析。结果 2 型糖尿病患者男性 及女性的Glu 、 GGT 水平与对照组比较，差异均有统计学意义(P0.05) ， 而 ALT 则无差异;男性和女性2 型糖尿 病患者中 GGT 浓度越出参考脏间的百分率分别是 13)奋和 16% ，明跟高于对照组。结论 GGT 对于2 型糖尿病 的早期珍断有…定意义。 关键词:Y嗣谷氨毗基转移酶;丙氨酸氨基转移酶;2 型糖服病 Prel切tinary inVIωtig翩。1000 the value of serwn GGT 朋d ALT for the 阳rly diagn侃is of type 2 diabetes mellitus SHEN Ch阴阳i ， WANG ÚJ咆则， WANG Me协ng. (Department 01 Clinícal Laborl创0厅， Shanghai F;伊h Peoples Hospital • Fudan University ,Shanghai 21ω240 ,China ) Abstract: Obj耐ve To investigate the clinical application value Of 脚rum gamma呐tamyltransfel栅 (GGT) and alanine aminotransfer脚(ALT) for the early diagnOsis Of type 2 diabet跚跚llitus. Meth叫s 2∞ patl日脚 with W阳 2di必et创 mellitus were enrolled in experiment group ( 1∞ males and 100 females). 2∞ healthy subjec恼 were enrolled as control group. The levels of serum glucose (Glu). GGT and ALT Of patients and healthy subj阴阳 were detected by Roche Modular autOmatic biochemistry analyzer system and the results were analyzed statistícally. R棚llts 咀le difference Of serum Glu and GGT between experiment 脚up and control grOup had statistical sí伊ificance ( P 0.05). 币lere wa.s nO difference Of A口 between experiment 锣Oup and contrOl group. 切le abnormalíty rates of GGT among male and female patienωwith type 2 diabet创 mellítus were 13% and 16~毛 respectively ， which were higher than those in control group. Conclusioøs GGT may be a marker for the earl