蛋白质网络中模块.pptVIP

(C) Triplet scoring notation. M1 = genes in module 1; T = genes in genome containing binding site for TF T; m1 = genes in M 1containing binding site for T (“target genes”); M1′= genes in M1 that do not contain a binding site for T (“non-target genes”); randomly selected genes from M1′; M2, m2, M2′ defined analogously. Aggregate target genes = (m1 ∪m2) or (m1∪m2∪IT) ; aggregate non-target genes =(M1′∪ M2′) or (M1′∪ I ∪ M2′); I and IT represent non-target and target genes, respectively, that are present in both modules. (D) Quartet scoring not