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双相抑郁是否有必要使用抗抑郁药物.pdf
• 170. Shanghai Archives of Psychiatry ,2011 ,Vo l. 23 ,NO.3
· Forum •
Forum: Use of antidepressants in bipolar depression
Is the use of antidepressants essential when treating
bipolar depression?
Yi Ru FANG
。i 附ctor Chief Psychiatrist, Division of Mood Di5Orders, Shanghai Mental Health Center; Director
Pro币es5Or, Management Center for Mood Disorder, Department of Psychiatry, Shanghai Jiao Tong University
School of Medicine, Shanghai , China.
E-mail: γirufan耐γahω. com. cn
There has recently been increased interest in sants in both the acute and maintenance phase of
bipolar depression , a serious disabling condition bipolar depression provide the following rationale:
with high morbidity,frequent recurrence and an el- ( failure to use antidepressants would decrease the
evated risk of suicide that is associated with a sub- likelihood and speed of remission of depressive
stantial burden of illnessll,2J . A research article and symptoms and , thus , unnecessarily increase the risk
commentary in the previous issue of the Shanghai of suicidal behavior; and ( there are no other ef-
Archives of Psychiatryl3,4J highlighted 50me of the fective method for treating depressìve episodes in
difficulties in distinguishing unipolar depressive dis- bipolar disorder. One study that suppo阳 this ap幡
l71
order and bipolar depressive disorder. To address proach followed 84 patients with a bipolar de-
this issue,we first need to understand that uni
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