抗感染抗体幻灯片.pptVIP

抗感染单抗药物 研究与开发 免疫系统是人体健康的防线，用以抵御细菌和其他微生物的侵袭，其中免疫球蛋白（抗体）在免疫保护中发挥重要作用。机体在病毒和细菌感染中以及感染后都将产生特异性抗体，该抗体可以与刺激它们产生的抗原决定簇发生特异性反应，具有重要的抗感染作用。 Active immunization. Traditional vaccines work by exposing patients to immunogens from infectious agents, prompting their immune systems to produce a range of anti-pathogen (polyclonal) antibodies. This approach is ideal for healthy populations, but works less well in immunocompromised patients or in patients whose infections take hold before the vaccine has a chance to work. Passive immunization. Polyclonal antibodies or mAbs are infused directly into patients’