药学专业英语ppt.pptVIP

Abstract 1 Study design 2 Results 3 Conclusions 4 Infantile spasms are a catastrophic form of pediatric epilepsy with inadequate treatment. Using an animal model, the Arx(GCG)10+7 mouse, we determined that brief estradiol (E2) administration during early postnatal development prevented spasms in infancy and seizures in adult mutants. Study design Effect of early E2 treatment on epilepsy in Arx mutants Effect of early E2 treatment on infantile spasms in mutants Effect of E2 treatment on cortical interneurons（中间神经元） Effect of E2 treatment on mRNA levels of Arx targets Neonatal E2 prevents epi