淤胆型肝炎的治疗(国外英文资料).doc

淤胆型肝炎的治疗 The treatment of choleroid hepatitis Western medicine: refers to a variety of reasons, including various hepatitis viruses, drugs, endocrine, autoimmune diseases, etc.) caused by intrahepatic bilirubin and excretion obstacles, lead to lasting not refund or progressive deepening jaundice, therefore silting bravery is a cause of many complex syndrome and pathogenesis, rather than individual disease. Etiology of western medicine: the cause of the occurrence of hepatic bile deposition in the liver of viral hepatitis is multifaceted. Intrahepatic bile duct injury, infection, hepatitis virus, intrahepatic inflammation, especially serious inflammation portal area make the capillary bile ducts in the liver, small bile duct, timid pipe connecting parts, Hector, leaf between bile duct pressure; Or bile is formed in these bile ducts, which can affect the discharge of bile. If high blood bilirubin (TBil 171 mu mo1 / L) duration is too long, liver cells have a large number of Bi1, especially not associativity Bil (DBil) deposition, inhibits Bil combined with glucuronic acid required for converting enzyme and microsomal enzymes, such as the activity of the enzyme, causes the Bil combined with obstacles, Bil combination and discharge all can happen cholestasis. In addition, in acute or chronic viral hepatitis, liver cirrhosis, deposition of bile type patients often have cholestasis factor (cholestaticfactor, CF) produce, endotoxin hematic disease, the secretion of bile duct mucosa thromboxane B2 (TXB2) a large number of growth and treated with hormone, the liver microcirculation, ultrastructure damage can be further cholestasis of jaundice and so the cause of cholestasis is very complicated. TCM etiology: if the type is acute hepatitis silting bravery, short duration, etiology and pathogenesis is more hot and humid: if the course of more than a month, or on the basis of chronic hepatitis, cirrhosis of silt, the disease because stasis hot junction each hair is yellow. (1)