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石墨炉原子吸收法测定替加环素中钯的残留量_王湘波
Central South Pharmacy. September 2015, Vol. 13 No. 9
[J]. 200028 2176-179. [J]. 201428 11
[11] . [J]. 1247-1251.
200239 2371-373. [14] . ICP-MS
[12] . -ICP-OES [J]. 2010
[J]. 201412121236-1239. 30 101852-1855.
[13] . -ICP-OES 2015-04-27 2015-06-18
*
410001
0 80 ng mL 1
1 1
r
0.99960.09 ng mL 0.31 ng mL 3
97.8%100.7%105.2%
R917 A 1672-2981(2015)09-0977-03
doi:10.7539/j.issn.1672-2981.2015.09.021
Determination of palladium residues in tigecycline by graphite
furnace atomic absorption spectrometry
*
WANG Xiang-bo, MA Xiao-ning , FAN Ya, PAN Zhen-yu, TANG Xu (Hunan Institute for Food and Drug Control,
Changsha 410001)
Abstract: Objective To establish a method to determine palladium resudyes in tigecycline. Methods A graphite fur-
nace atomic absorption spectrometry method was used to determine palladium residues in tigecycline. Results Pal-
ladium showed a good linearity at 0 60 ng mL 1 (r 0.9996). The LOD and LOQ were 0.09 ng mL 1 and 0.31
1
ng mL , respectively. The average recovery of 3 concentrations was 97.8%, 100.7%, and 105.2%. Conclusion
The method is specifi c, and can be used to determination of palladium residues in tigecycline.
Key words: graphite furnace atomic absorption spectrometry; tigecycline; palladium; residue
tigecycline 2010 [8]
glycylcyclines
[1]tRNA
[2]
[3] 1
1.1
[4]
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