碳酸二甲酯作甲基化试剂合成2_6_二氯苯甲醚.pdfVIP

277 精 细 化 工 Vol. 27, No. 7 2 0 1 0 7 FINE CH EM ICAL S July 2 0 1 0 2 , 6 1 1 1 1, 2* 2 董燕敏 , 尹振燕 , 程 琦 , 陈兴权 , 赵天生 ( 1. , 213164; 2. , 750021) : ( DM C), 2, 6( DCP) , ( PTC) , 2, 6 ( DCA ) PTC , : 400( PEG - 400) PTC, x ( PEG- 400) = 02% , n ( DMC) n ( DCP) n ( K CO ) = 010050003, 150 , 5 h, , DCA 2 3 873% , DCP 100% , , : ; 2, 6; 2, 6; : TQ426 : A : 1003- 5214( 2010) 07- 0667- 05 Synthesis of 2, 6D ich loroanisole w ith D im ethyl Carbonate asM ethylating Agent 1 1 1 1, 2* 2 DONG Y anm in , Y IN Zhenyan , CHENG Q i, CHEN X in quan , ZHAO T ianshen ( 1. J iang su K ey L a bora tory of F ine P etro chem ica l E ng ineering, Changzhou Un iv ersity, Changzhou 2 13164, J iang su, Ch ina 2. K ey L aboratory of E nergy R esource and Chem ical E ng ineering of N ingx ia Un iv er sity, Y inch uan 75002 1, N ingx ia, Ch ina ) Ab stract 2, 6D ich loroanisole( DCA) w as prepared from 2, 6dich lorophenol( DCP) in the presence of potassium carbonate ( K CO ) and the phase transfer catalyst( PTC), usin dmi ethyl carbonate ( DMC) 2 3 as methylatin rea ent instead of the conventional tox ic rea ents. The best y ield( 873% ) of DCA and the conversion ( 100% ) ofDCP w ere obtained under optmi ized cond itions that polyethylene lycol 400 ( PEG- 400) w as used as PTC, x ( PEG- 400) = 02%, n ( DMC) n ( DCP) n ( K CO ) = 01005