福辛普利与依那普利治疗轻中度高血压病的疗效比拟(国外英文资料).docVIP

福辛普利与依那普利治疗轻中度高血压病的疗效比较(国外英文资料) Fusimpley compared the efficacy of the treatment with the treatment of mild hypertension 2010-08-02, the king of the fine horse, xu wei Yang 【 abstract 】 objective to compare the curative effect and safety of fusimpley and iappuri for the treatment of mild hypertension. Methods open randomized controlled trials, after 2 weeks placebo period, 139 patients with mild-to-moderate hypertension in 8 weeks of treatment, 1 times a day taking the cinepolis 10 mg (74 cases) or enalaprilat 5 mg (65 cases), after 2 weeks if diastolic blood pressure 90 mmHg or double dose, 4 weeks if it is still invalid add hydrochlorothiazide 25 mg per day. Both groups of drugs significantly lower blood pressure (P 0.001); Fuxin was 90.1 per cent effective, and the innappe rate was 88.9% (P 0.05). The patients were 38% and 51 percent of the patients with diuretics (P 0.05). The value of the valley peak was 59.9 percent, and in the area of enna was 47.1 percent. The most common adverse reactions were cough, 4 in each group. Conclusion it is an effective, safe and tolerable antihypertensive drug, and can maintain 24 hours of blood pressure per day. 【 keywords 】 high blood pressure angiotensin conversion enzyme inhibitors Comparison of fosinopril and enalapril in the treatment of mild to moderate essential hypertension Zhu Junren, Wang Xianyan, Xu Wei, et al. Zhong Shan Hospital, Shanghai Medical University, Shanghai 200032 【Abstract 】　Objective　To compare the efficacy and safety of fosinopril and enalapril in the treatment of mild to moderate hypertension. Methods　Following a 2-week placebo period, 139 patients entered an 8-week randomized, parallel study with either 10 mg fosinopril (n=74) or 5 mg enalapril (n=65) once daily. Dose doubling and the addition of dihydrochlorothiazide 25 mg once daily were required if diastolic blood pressure ≥90 mmHg at week 2 and week 4 respectively. Results　Blood pressure were significantly reduced in both groups (P0.001). Ther