肝脂肪变和脂肪肝的病理变更(国外英文资料).docVIP

肝脂肪变和脂肪肝的病理变化(国外英文资料) 1 alcoholic fatty liver This type of fatty liver was caused by alcohol, and alcohol consumption and alcohol consumption were not strictly parallel to subsequent liver damage. The daily alcohol intake of 60g of alcohol was found to be fatty liver, but was fully recovered within weeks of abstinence. However, if drinking more than 160g of alcohol per day, fat hepatitis can occur. The pathogenesis of alcoholic fatty liver disease is not clear, and may be related to the following factors: the damage to hepatic cell by alcohol metabolite acetaldehyde; The accumulation of peroxide in cells; Alcohol interferes with the antivirus system; The liver reticular tissue dysfunction, accompanied by Kupffer cell purification, decreased. In morphology, alcoholic fatty liver is characterized by large lipid droplets in hepatic cells, which are the focal distribution and are most pronounced in the central section of the liver. Individual excessive fat necrosis of liver cells dissolved, replaced by fat sex granulation is swollen, the latter by around with lymphoid cells, tissues and cells of lipid droplets and eosinophilic cells. If the lipid granuloma is a multi-tuberous structure, it should be accompanied by significant fibrosis. Non-specific reactive hepatitis is visible in the manifold. Toxic fatty liver Liver damage caused by a chemical (toxicant or drug). Some substances themselves, or their metabolites, can damage liver cells directly by physical chemistry, called direct absolute hepatotoxin. It is such as tetrachloride, chloroform, mushroom, phosphorus, etc. Some material not to damage liver cells by poison itself, but make certain substance metabolism disorder, caused liver cell fatty change or necrosis, referred to as indirect absolute liver toxins. Such poison mainly for drugs, such as cell inhibitors (drug metabolism), antibiotics (tetracycline), analgesic (acetaminophen) and the anti-rheumatism medicine (bute), etc. Welcome to the pearl grass Fatty liv