2014HFPEF中国共叫(国外英文资料).docVIP

2014HFPEF中国共识(国外英文资料) Chronic HF - PEF diagnosis and treatment HF - PEF is often referred to as diastolic heart failure and its pathophysiologic mechanism is not clear, now think that the disease is due to left ventricular diastolic active relaxation ability damage and reduced myocardial compliance, namely the increase of stiffness (myocyte hypertrophy with interstitial fibrosis), left ventricular diastolic filling in damaged, the decrease of cardiac, increased left ventricular end-diastolic pressure occurring in the course of heart failure. The disease can be found in the same way as the contraction dysfunction, but it can also exist separately. HF - PEF accounts for 50% (40% to 71%) of heart failure. The prognosis is similar to that of HF - REF. Asymptomatic left ventricular diastolic dysfunction associated with heart failure incidence and case fatality rate, from the United States a epidemiological survey found that the community crowd asymptomatic mild left ventricular diastolic dysfunction of 2 l %, the relation between left ventricular diastolic dysfunction (7%). One, HF - PEF diagnostic criteria The diagnosis of this disease should be fully considered in the following two aspects. Major clinical manifestations: the symptoms and signs of a typical heart failure; LVEF is normal or slightly lower (= 45%), and the left ventricle is not large; There is evidence of structural heart disease (such as left ventricular hypertrophy, enlarged left atrium) and (or) diastolic dysfunction; Echocardiography is an echocardiographic examination of unintentional valve disease, which can be used to exclude heart disease, hypertrophic cardiomyopathy, and limited type (infiltrating) cardiomyopathy. The LVEF standard of the disease is not yet unified. LVEF in 4 l % ~ 49% called critical HF - PEF, its population characteristics, treatment and prognosis were similar to HF - REF, suggesting the LVEF 50% as clinical diagnostic criteria may be better. In addition, some patients have s