“血小板卫星”气象(国外英文资料).docVIP

“血小板卫星”现象(国外英文资料) The effect of platelet satellite phenomenon on counting Alvin chung Use of anticoagulant EDTA - 2 k, a few patients blood smear tail can see clusters of aggregation of platelet, sometimes also can see the platelet adhesion on white blood cells, form the so-called platelet satellite, cause the blood cell analyzer low platelet count. Platelets are aggregated into clumpy platelets that form satellite phenomena around neutrophils EDTA induced platelet satellite phenomena (platelet satellitism), pseudo thrombocytopenia caused the EDTA dependency thrombocytopenia (PTCP) should be widely attention, the clinical incidence of about 0.09% to 0.09%. Because of using EDTA salt (EDTA salt powder anticoagulants, ethylenediamine tetraacetic acid) powder anticoagulants, in blood, as the immune mediated antiplatelet autoantibodies can appear in the cold, make the platelet agglutination phenomenon with each other. The EDTA relies on a cold platelet antibody that ACTS directly on the platelet membrane glycoprotein IIb/IIIa. At the same time, this antiplatelet binding self-antibody Fc can be associated with a single nucleus cell or a Fc receptor in the lymphocyte membrane, and a satellite phenomenon occurs. The phenomenon of decreased pseudoplatelet count was observed when the platelet aggregation appeared and the satellite was detected. There are several reasons for this: There are problems with coagulation. It may be that the anticoagulation ratio is not right, and it can cause satellite phenomena. 2. Place time is too short, it is also testing classification in 25 minutes important cause of unstable plaque, EDTA anticoagulant and platelet clotting factor reaction takes time, this time with the increase of temperature and shorten, this also is a time when the weather turns cold reason for the easy problems. The causes of platelets are also linked to some hidden antigens on the surface of the platelets. Only when EDTA exists, the bodys IgG or IgM antibodies can reac