胺碘酮的血汗管感化(国外英文资料).docVIP

胺碘酮的心血管作用(国外英文资料) The cardiovascular function of amiodarone Amiodarone for anti-arrhythmic drugs in decades of years of clinical application, application status and importance of rising, the emergence of this situation is no accident, this has to do with amiodarone is closely related to the multiple beneficial effects in the body. Todays coronary heart disease, high blood pressure, cardiac arrhythmia is the three most common diseases, cardiovascular field and amiodarone combined expansion crown, step-down, anti-arrhythmic triple role is rare. In order to make use of iodide, the clinician must have a thorough understanding of its various cardiovascular functions, which can be more active and effective. The role of iodide in the cardiovascular system Dilation of coronary arteries and myocardial ischemia Amiodarone originally listed as a angina drug resistance in clinical application, the application in a few years its identity change into a anti-arrhythmic drugs, therefore, little detail the function of its resistance to myocardial ischemia. The effect of amiodarone against myocardial ischemia from two aspects, one is flabby vascular smooth muscle, direct expansion coronary blood vessels, reduce coronary resistance, increase myocardial blood supply; It is the antagonism of noncompetitive adrenalin, and the inhibition of only receptors can make the coronary arteries expand. Animal studies have shown that after intravenous injections of 5mg/kg of iodide, the expansion of the coronary artery can occur. Clinical applications of oral amiodarone for Labour angina, coronary spasm caused by variant angina pectoris have therapeutic effect, and intravenous caused by unstable angina, and coronary artery spasm angina has a therapeutic effect. It has positive effect in reducing the area of myocardial infarction and improving the prognosis of patients with heart disease. The obvious anti-myocardial ischemia of amiodarone is strongly recommended for the mechanism and reason for the