荧光试剂Indo_1的合成.pdfVIP

2008 16 V o.l 16, 2008 5 , 503~ 507 Ch inese Journa l of Synthe tic Chem istry N o. 5, 503~ 507 * 荧光试剂 ndo1的合成 徐若千, 郭 媛, 宋丹梅, 贺怀贞, 陈康裕 ( , 710069) : , 10 ndo1, 1H NM R, R M S : ; ndo1; : O 626. 1 : A : 100515 11( 2008) Synthesis of Fluorescence Indicator Indo1 XU Ruoq ian, GUO Yuan, SONG Danm ei, HE H uaizhen, CHEN K angyu ( D epartm ent of Chem istry, N o rthw est U niversity, X i! an 7 10069, Ch ina) Abstract: A fluorescence ind icator, indo1, w as synthesized from onitro lpheno l by a tenstep reac 1 tion. T he structure w as characterized by H NM R, R and M S. K eywords: fluorescence indicator; ndo1; synthesis ( KB r); MA LD TOF M S Ax mi a CFR Plus [ 1] [ 2] 20 80 T sien ; PE2400 EGTA, BAPTA , 4, ; 2+ C a ndo1 [ 3~ 7] 1. 2 合成 , 2+ ( 1) ( 3) C a [ 8~ 9] [ 10 ] ( 1) ( 4) , 10 2 + 2. 43 g( 11mm ol), , Ca ndo1 1 5 ∀ HNO3 1m L, , 5 ∀ ( Schem e 1) , H NMR, R M S