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哺乳动物红细胞专题知识总结(国外英文资料)
哺乳动物红细胞专题知识总结(国外英文资料)
Summary of the special knowledge of red blood cells in mammals
Biological group
High school stage knowledge of red blood cells appeared again and again, especially mammalian RBC, province college entrance examination, the national college entrance examination questions several times throughout the years with red blood cells as background check the students ability level, which highlights the red blood cells, the importance of knowledge. In this paper, we will summarize and look at the role of the brick and jade in our colleagues.
1, shape and color: double concave structure, red. The diagram below:
Second, production: the hematopoietic stem cell division in the bone marrow and the differentiation form. The diagram of its differentiation is as follows:
Gene mutation -- sickle cell anemia:
Cause: 1, in the process of the formation of red blood cells and hematopoietic stem cells differentiation consistently split to form new stem cells, gene mutation, if this process is likely to trigger type sickle cell anemia. The diagram is as follows:
Summary: it is a recessive genetic disease. The blood red blood cells of the person with the disease are shown as sickle, and they carry oxygen only half as much as normal red blood cells.
3, diagnosis:
(1) cell level: taking a blood cell, optical microscopy, to observe the shape of the red blood cells;
(2) molecular level: a probe made from the gene of beta-globin.
Typical questions:
The genetic diseases of single gene can be diagnosed early by the hybridization of nucleic acid. Sickle cell anemia is a single genetic disease with a high incidence of disease in the Mediterranean. The genotype of the known red blood cells was BB, BB, and the genotype of the patient with sickle cell anemia was BB. A couple were tested for the disease-causing gene, and prenatal diagnosis was made early in pregnancy in order to produce healthy children. The image below shows the prenatal nucleic acid hybridization and the results of
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