宫颈小细胞神经内分泌癌1例报告及文献回顾(国外英文资料).docVIP

宫颈小细胞神经内分泌癌1例报告及文献回顾(国外英文资料) Cervical at 4 o clock position is the size of a walnut, focally cauliflower shaped, qualitative hard, contact hemorrhages, part of the smooth, from normal size, double annex no abnormalities are found. Pathological biopsy: cervical carcinoma, small cell type low differentiation possibility of neuroendocrine carcinoma, clinical staging Ⅰ a ~ Ⅰ bG3. On February 15, 2006 to be applied under the general anesthesia combined epidural anesthesia with generalized total hysterectomy + pelvic lymph node cleaning operation, intraoperative see normal uterine size, smooth surface, bilateral ovaries, fallopian tubes form normal, abdominal cavity without ascites, did not see intra-abdominal metastases, widely carries out the uterus resection and pelvic lymph node cleaning and good postoperative recovery. Postoperative pathological return: cervical cell neuroendocrine carcinoma; Tumor cell invasion and muscular layer at 4, 5, and 5 points in the cervix; Cervical cancer, the endometrium; There was no cancer in the vaginal end, no tumor cells were found in the double attachment, and the left closed hole nodes were nodules (1/2), and the remaining lymph nodes were not. 16 days after surgery, the PE regimen was chemotherapy. Then there is bilateral iliac lymphocyst, the treatment of the disease. The interval 4 weeks chemotherapy 1 time, the total line 6 courses, the regular follow-up did not see the abnormality. The patient underwent six rounds of chemotherapy after the operation, and the cumulative amount of drugs was 720 mg, and the VP of -16, 000 mg. During chemotherapy, two myeloid inhibition was more apparent, and the treatment of leukocyte therapy (GSF) was adopted. 1 drug liver injury, the treatment of the liver and other treatments soon improved. The tumor serum marker ca-125, CP2, SA and so on are all normal. X-ray chest X-ray and ecg are normal. Gynaecological color: pelvic cavity, bilateral iliac lymphocyst. Abdominal color: the spleen and pancr