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紫外分光光度法测定盐酸麻黄素注射液含量(国外英文资料)
紫外分光光度法测定盐酸麻黄素注射液含量(国外英文资料)
The ultraviolet spectrophotometry measures the levels of the injection of ephedrine
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The ultraviolet spectrophotometry measures the levels of the injection of ephedrine
Keywords: ephedrine; Visible and ultraviolet spectrophotometry
[abstract] objective: to explore new methods for determination of ephedrine hydrochloride injection in order to adapt to the need of clinical medicine more quickly and accurately. Methods: with different manufacturers and different batches of ephedrine hydrochloride injection for test samples, the use of standard of ephedrine in reference substance, using ultraviolet spectrophotometer to measure standard of maximum absorbance, and the relationship between concentration and absorbance, the regression equation, measuring its recovery. The content is compared with the pharmacopoeia. Results: in 256 had the biggest absorption, plus or minus 1 nm to 256 nm for measuring wavelength, concentration and absorbance of ephedrine hydrochloride in standard curve linear range of 0.2 ~ 0.2 mg/ml (r = 0.999), the average recovery was (100.31 + 1.02) %, two methods of determination results there was no significant difference (P 0.05). Conclusion: uv spectrophotometry can be used as a new method for determination of ephedrine.
[Chinese book data classification classification] O 657.32 [literature id] A
[article number] 1000-2200 (2000) 2005-0380-02
Ephedrine hydrochloride is a quasi adrenalin medicine, at present the content determination method for the disease and its preparation are non-aqueous titration method of [1], silver [1] [2] and neutralization method. Using ultraviolet spectrophotometry [1], this paper determined the content of ephedrine hydrochloride injection [3], and with the 1995 edition of pharmacopoeia nonaqueous titration, this.
1 material and method
Instrument du-640 ultraviolet spectrop
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