妊娠合并亚临床甲状腺功能减退对孕期并发症与`妊娠结局影响.docVIP

妊娠合并亚临床甲状腺功能减退对孕期并发症及妊娠结局的影响 　　[摘要] 目的 分析妊娠合并亚临床甲状腺功能减退对孕期并发症及妊娠结局的影响。方法 整群选取该院2014年6月―2015年6月接收的95例妊娠合并亚临床甲减孕妇作为观察组，并选取同期95例正常妊娠孕妇作为对照组。两组孕妇入院后均常规进行产前检查和保健，定期检测血压、血糖水平，观察并记录两组孕期并发症情况和妊娠结局。 结果 观察组妊娠期高血压、妊娠期糖尿病发病率分别为12.63%、15.79%，显著高于对照组的4.21%、6.32%，差异有统计学意义（P0.05）。结论 妊娠合并亚临床甲减可增加孕期并发症和不良妊娠结局的风险，临床应注意定期产检，严格防治，以期最大程度改善妊娠结局 [关键词] 妊娠；亚临床甲状腺功能减退；孕期并发症；妊娠结局 [中图分类号] R714.25 [文献标识码] A [文章编号] 1674-0742（2016）06（a）-0082-02 [Abstract] Objective To analyse the effect of subclinical hypothyroidism on pregnancy complications and pregnancy outcome.Methods Group selection 95 cases of pregnant women with subclinical hypothyroidism received from June 2014 to June 2015 in our hospitalin June were selected as the observation group， and at the same time 95 cases of normal pregnant women were selected as the control group.The two groups of pregnant women were treated with routine antenatal examination and health care， regularly receiving blood pressure and glucose level.Pregnancy complications and pregnancy outcome of the two groups were observed and recorded. Results The incidence rates of gestational hypertension， gestational diabetes in the observation group were respectively 12.63%， 15.79%， significantly higher than those of the control group 4.21%， 6.32%， with significant difference statistically（P0.05）. Conclusion The risk of pregnancy complications and adverse pregnancy outcomes can be increased by subclinical hypothyroidism.Therefore， attention should be paied to regular production inspection and strict control in clinical treatment to improve the outcome of pregnancy to the greatest degree. [Key words] Encyesis；Subclinical hypothyroidism ； Pregnancy complications；Pregnancy outcome 甲状腺功能减退症（甲减）是常见的内分泌疾病，是多种因素引发的甲状腺激素（TH）不足所致，高发人群为育龄期女性[1]。亚临床甲状腺功能减退症（亚临床甲减）又称轻微型甲减，患者血清游离甲状腺素（FT3，FT4）水平正常，仅促甲状腺素（TSH）升高，表现为无或有轻微甲减症状。TH与机体的物质、能力代谢及生殖等重要功能密切相关，若发生甲状腺功能异常则会使机体代谢异常，导致血液、消化、心血管、肌肉神经系统等全身性疾患；且TH还有促进生长发育的生物作用，对于妊娠女性这一特殊群体，若发生甲减则可能对孕妇和胎儿的健康、智力发育造成不良影响[2]，故妊娠期甲状腺疾病已成为近年来医学界的热门