琥珀酸去甲文拉法辛缓释片的制备及体外释药特性研究.pdf

与渗透泵技术联合应用，在改善难溶性药物水溶 action of nitrendipine/MCM-41 drug loading system [J]. Asian J Chem, 2012, 24(2): 777-783. 性的同时，能够控制药物以近零级的速率释放， [8] SAREEN S, MUTREJA V, PAL B, et al. Homogeneous 既克服了药物释放的突释问题，又获得了控释的 dispersion of Au nanoparticles into mesoporous SBA-15 exhibiting improved catalytic activity for nitroaromatic 效果，提高了药物的口服吸收，增加了疗效。 reduction [J]. Microporous Mesoporous Mater, 2015, 202(15): 219-225. REFERENCES [9] HILL A, GEIßLER S, WEIGANDT M, et al. Controlled delivery of nanosuspensions from osmotic pumps: Zero order [1] QUAN P, SHI K, PIAO H, et al. A novel surface modified and non-zero order kinetics [J]. J Control Release, 2012, nitrendipine nanocrystals with enhancement of bioavailability 158(3): 403-412. and stability [J]. Int J Pharm, 2012, 430(1/2): 366-371. [10] LIU D, YU S, ZHU Z, et al. Controlled delivery of carvedilol [2] ZHANG Y Z, WANG H, GAO C Q, et al. Highly ordered nanosuspension from osmotic pump capsule: in vitro and in mesoporous carbon nanomatrix as a new approach to improve vivo evaluation [J]. Int J Pharm, 2014, 475(1/2): 496-503. the or