1例慢性肾功能不全患者使用头孢他_省略_左氧氟沙星致抗生素脑病的药学监护_石壬伟.pdf

1例慢性肾功能不全患者使用头孢他啶和左氧氟沙星致抗生素脑病的药学监护 ＊ 石壬伟 （常州市第七人民医院药事科，江苏常州 213011） 中图分类号 R978.1；R969.3 文献标志码 B 文章编号 1001-0408（2013）28-2648-03 DOI 10.6039/j.issn. 1001-0408.2013.28.20 摘 要 目的：为临床药师参与肾功能不全及其合并症的药学监护提供参考。方法：详细描述临床药师对1例慢性肾功能不全患 者使用头孢他啶和左氧氟沙星后致抗生素脑病实施药学监护的全过程。结果：通过临床药师实施药学监护，该患者相关不良反应 症状得到有效控制。结论：对于肾功能不全患者，临床药师尤其要注意及时发现和处理药物可能引起的不良反应，以有效减少其 给患者带来的危害。 关键词 临床药师；慢性肾功能不全；头孢他啶；左氧氟沙星；抗生素脑病；药学监护 Pharmaceutical Care for a Renal Insufficiency Patient with Encephalopathy Induced by Ceftazidime and Levofloxacin SHI Ren-wei（Dept. of Pharmaceutical Affair ，Changzhou Seventh People ’s Hospital ，Jiangsu Changzhou 213011， China ） ABSTRACT OBJECTIVE ：To provide reference for clinical pharmacists participating in pharmaceutical care for a renal insuffi- ciency patient with encephalopathy induced by antibiotics. METHODS ：The process of pharmaceutical care for a renal insufficiency patient with encephalopathy induced by antibiotics receiving ceftazidime and levofloxacin by clinical pharmacist were described in details. RESULTS ：Related ADR could be controlled effectively by pharmaceutical care. CONCLUSIONS ：Clinical pharmacitsts particularly need detect and treat drug-induced ADR in patients with renal insufficiency in time ，in order to reduce the harm to pa- tients. KEY WORDS Clinical pharmacitsts ；Chronic renal insufficiency ；Ceftazidime ；Levofloxacin ；Encephalopathy induced by antibi- otics ；Pharmaceutical care 中用量和患者术后疼痛等不良反应。喷他佐辛的镇痛作用增 （8）：753. 强了患者对手术刺激的耐受能力，减少了因患者体动等因素 [ 3] Moerman AT ，Struys MM ，Vereecke HE ，et al. Remifent- 导致检查操作被迫中止的情况。本研究中P1-4组麻醉效果总 anil used to supplement propofol does not improve quality 体来说好于C 组，且P1-4组丙泊酚诱导剂量和用药总量更少，因