炎琥宁在小儿手足口病治疗中应用价值.docVIP

炎琥宁在小儿手足口病治疗中的应用价值 　　[摘要] 目的 探讨炎琥宁在小儿手足口病治疗中的应用价值。 方法 从我院2014年11月～2015年11月诊治的手足口病患儿中抽取86例作研究对象，将其随机分为对照组（n=43）和观察组（n=43）。对照组患儿接受阿昔洛韦治疗；观察组则在阿昔洛韦治疗的基础上应用炎琥宁。比较两组患儿的治愈率、治疗总有效率、退热时间、皮疹消退时间和不良反应发生率。 结果 观察组患儿治愈率为86.05%，治疗总有效率为97.67%，退热时间为（2.47±1.32）d，皮疹消退时间为（3.44±1.93）d；对照组患儿治愈率为48.84%，治疗总有效率为88.37%，退热时间为（4.61±1.85）d，皮疹消退时间为（5.74±3.05）d。两组患儿治愈率、治疗总有效率、退热时间和皮疹消退时间比较，差异有统计学意义（P0.05）。 结论 炎琥宁治疗小儿手足口病可显著提高患儿治愈率，并加速患儿皮疹、高热等症状消退进程，且不会增加患儿不良反应，可作为小儿手足口病理想治疗药物 [关键词] 炎琥宁；小儿手足口病；治愈率 [中图分类号] R725.1 [文献标识码] A [文章编号] 1674-4721（2016）05（b）-0105-03 [Abstract] Objective To explore the application value of Yanhuning in treating infantile hand-foot-mouth disease. Methods 86 hand-foot-mouth disease children from November 2014 to November 2015 of our hospital were selected and were divided into control group（n=43） and observation group（n=43） in random.Children in control group were used acyclovir，and children in observation group were used Yanhuning on the basis of acyclovir.The cure rate，treatment total effective，defervescence time，rash disappeared time and the incidence rate of adverse effects between two groups were compared. Results The cure rate，treatment total effective，defervescence time and rash disappeared time in observation group were respectively 86.05%，97.67%，（2.47±1.32）d and （3.44±1.93）d，which were respectively 48.84%，88.37%，（4.61±1.85）d and （5.74±3.05）d in control group.All of the cure rate，treatment total effective，defervescence time and rash disappeared time between two group had statistical significance（P0.05）. Conclusion Yanhuning has obvious application value in infantile hand-foot-mouth disease，which can increase the child patient cure rate，promote recession of rash and hyperpyrexia and not increase the adverse effects.It can be an ideal treatment drug for infantile hand-foot-mouth disease. [Key words] Yanhuning；Infantile hand-foot-mouth disease；Cure rate 小儿手足口病，属于小儿出疹性病症，主要由肠道病毒感染所致，具有感染性强、传播快等特点，可在小儿中表现出爆发型或散发型流行[1]。小儿手足口病主要临床症状为发热、臀部和手足部位水疱、口腔疱疹、斑丘疹和溃疡等，少