作用于gaba受体杀虫剂药理学.pptVIP

第六章 作用于GABA受体杀虫剂 1、 GABA-receptor GABA (γ-aminobutyric acid ) is a true neurotransmitter. GABAs role is that of the primary inhibitory neurotransmitter. GABA achieves this by effecting the actions of the GABA receptor, a 5 subunit ion transporter. 1. GABA-receptor 1. GABA-receptor 1. GABA-receptor 1. GABA-receptor 1. GABA-receptor When GABA binds to the GABA receptor, the subunits of the receptor open and there is an influx of chloride ions. This influx restores the electrical potential of the neuron and thereby decreases the likelihood that the neuron will depolarize and