退行性脊柱侧凸和骨质疏松的关系探讨.pdfVIP

解放军医药杂志2014年10月 第26卷 第10期 Med PharmJ Chin PLA,Vol.26,No.10,Oct.2014 ·27 · ·论著 · 退行性脊柱侧凸和骨质疏松的关系探讨 楼肃亮,赵志芳,李小娟 　 　 [摘要]　 目的　 探讨退行性脊柱侧凸(DS)与骨质疏松(OP)的相关性。 方法　 选取2004 年1月—2014 年1月 在解放军117 医院门诊及住院的DS患者116例设为DS组,另选取同期来院就诊的非腰椎侧凸的腰痛患者116例为 对照组,测定Cobbs角、腰椎(腰1~4)及股骨颈、股骨粗隆和Wards三角T值,分析患者OP发病率,年龄、Cobbs角与 对应T值的相关性。 结果　 DS组骨质疏松发病率显著高于对照组(P0．01);DS组腰椎(腰 1~4)、股骨颈、股骨粗 隆和Wards三角区骨密度T值与对照组比较差异均有统计学意义(P0.05);DS组T值(绝对值)与年龄存在正相关 关系(r=0.421,P0．01);DS患者腰椎及股骨近端各部位的T值与侧凸Cobbs角无相关性(P 0．05)。 结论　 OP 是DS发病的危险因素,同时骨质疏松程度随着年龄的增大而增加,但与侧凸程度无明显相关。 　 　 [关键词]　 脊柱侧凸,退行性;骨质疏松;年龄因素 [中国图书资料分类号]　 R682.3　 　 [文献标志码]　 A　 　 [文章编号]　 2095-140X(2014)10-0027-03 [DOI]　 10.3969/ j.issn.2095-140X.2014.10.008 Relationship between the Degenerative Scoliosis and Osteoporosis 1 1 2 LOU Su-liang ,ZHAOZhi-fang ,LI Xiao-juan (1. Department of Osteology　 Treatment Centre of Rachial Surgery of PLA,117 Hospital of PLA,Hangzhou 310013,China;2. Department of Radiology,Naval General Hospital of PLA, Beijing 100048,China) [Abstract]　 Objective　 To investigate the relationship between the degenerative scoliosis (DS) and osteoporosis (OP).Methods　 A total of 116 DS patients duringJanuary2004 andJanuary2014 were chosen as DS group,and 116 lumbago patientswithout DS at the same periodwere selected as control group. T values of Cobbs angle,lumbar spine (lumbar 1-4),femoral neck,trochanter andWardStrianglewere detected,andthe relationshipsbetweenthe incidence rate of OP,ageandCobbsanglewiththecorrespondingTvalueswerealsoanalyzed. Results　 Theincidencerateof os- teoporosis in DS groupwassignificantlyhigherthanthatincontrolgroup (P0．01);thedifferencesinTvaluesoflum- bar spine (lumbar 1-4),femoralneck,trochanterandWardstriangleinDSgroupwerestatistically significantcompared withthoseincontrolgroup (P0．05);TvaluesofDSgroupwerepositivelycorrelatedwithage (r=0.421,P0．01)