某院2015年抗菌药物使用情况探析与合理用药评价.docVIP

某院2015年抗菌药物使用情况分析及合理用药评价 　　[摘要] 目的 了解某院抗菌药物的使用情况以及对用药合理性进行评价，为合理使用抗菌药物提供参考。 方法 按限定日剂量（DDD）法，对某院2015年度所有抗菌药物排序前20位的药物销售金额及用药频度（DDDs）进行统计，得出排名前3位的药品并进行分析，了解该院抗菌药物的总体使用情况。对该年度的医嘱处方点评资料进行收集统计，并结合具体处方实例说明该院的不合理用药情况，分析可能原因并给出可行建议。 结果 销售金额排名前3位的药物分别是注射用头孢呋辛、注射用头孢替安、注射用头孢吡肟，用药频度（DDDs）排名前3位的药物分别是注射用头孢呋辛钠、头孢呋辛酯胶囊、小檗碱片。从该院2015年抗菌药物专项处方点评结果统计可看出该院在抗菌药物使用方面存在药物选择不当（占36.58%）和用法用量不规范（占28.01%）等问题。 结论 抗菌药物在该院临床使用基本合理，但也存在不足之处，希望通过专项治理和药师干预，加强抗菌药物的使用监督和管理，促进合理用药 [关键词] 抗菌药物；用药分析；合理用药；处方点评 [中图分类号] R95 [文献标识码] A [文章编号] 1673-7210（2016）10（b）-0115-04 [Abstract] Objective To learn about the use of antibiotics in a hospital and evaluate rational use of drugs， so as to provide a reference for rational use of antibiotics. Methods By the defined daily dose （DDD）， sales amount and DDDs of top 20 antibiotics among the total of the year 2015 in a hospital were counted to get and analyze the first three places， to learn about overall use of antibiotics in this hospital. Materials on reviewing prescription instructions for the year were collected to show irrational drug use in this hospital with specific prescription instances， possible causes were analyzed and practical recommendations were given. Results The top 3 antibiotics in respect of sales amount were Cefuroxime sodium for Injection， Cefotiam for Injection and Cefepime for Injection， the top 3 antibiotics in respect of DDDs were Cefuroxime sodium for injection， Ceruroxime axetil Capsules and Berberine Tablets. According to statistical results of special prescription comments on antibiotics in this hospital for the year of 2015， there was some non-standard selection （36.58%）， usage and dosage （28.01%） of antibiotics in the hospital. Conclusion The antibiotics were basically reasonable for clinical use in the hospital， but there were still shortcomings. It is expected that supervision and management of antibiotics can be further strengthened through specialized administration and intervention of pharmacists， thus promoting rational use