中西医结合治疗原发性肾病综合征的系统评价.pdfVIP

成都中医药大学2006 级硕士论文 ABSTRACT Objectives：To evaluate the benefits and harms Traditional Chinese Medicine (TCM) combing with west medicine in patients with primary nephritic syndrome （PNS ）. Review systematically whether there is enough existing Evidences that TCM is effective and safe in the treatment of the patients With west medicine Methods ：We searched the Cochrane Controlled Trials Registe(CCTR)( The Cochrane Library issue 4 2008)、 MEDLINE(1997to2008), and China National Konwledge infrastructure (CNKI), Chinese VIP datebase （VIP ）,WanFang data .The Chinese journals related to TCM in 2008 searched by hand .Two authors independently assessed trial quality and extracted data from these Randomized Controlled Trails, then imported them into the Mete-analysis by Rev.Men 4.2.2. Results ：26 studies (1950patients) were identified. The results of Mete-analysis indicated: there are evidences to support that using TCM comding with west medicine is better than west medicine only on symptom physical sign and increasing the plasma levels of albumin and in decreasing 24-hour proteinuria and the plasma levels of total cholesterol and 、recurrence rate 、side effect. but the methododlogical quality is considered low in these stulevels of prevention. Conclusions ：By the result of this study , Chinese medical herds combining with Prednisone and/or Immunosuppressant more effective than simplex west medicine. However, the evidence is not enough strong because of the low qualities of trials, the small sample sizes and other defect 。 Kedwords ：the Traditional Chinese Medicine Prescription Primary Nephritic Syndrome Prednisone and/or Immunosuppressant Randomized Controlled Tra