李利民细胞损伤20102.ppt

* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * Reprogramming With Four Transcription Factors A Revolution in Pathology ? Reverse Development Biology ? PNAS, August 31, 2009 * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * iPS cells Reprogrammed Adult Cells Treat Sickle-cell Anemia In Mice Rudolf Jaenisch MIT Mature B Cells Reprogrammed To Stem-cell-like State Rudolf Jaenisch MIT Rudolf Jaenisch MIT New Technique Produces Genetically Identical Stem Cells Genes Involved in Stem Cell Diff