透析患者残余肾功能与其保护.pdf

医药专论 世界临床药物 WORLD CLINICAL DRUGS Vol.30 NO.2 ·综 述· 透析患者残余肾功能及其保护 萧杏贤，张益民* 510120 （中山大学附属第二医院肾内科，广州 ） 摘要：残余肾功能(RRF)是影响透析患者存活率的重要因素。本文回顾血液透析以及腹膜透析患者保存RRF 的重要性以及 RRF ACEI II 的评估方法、影响因素与保护措施等。阐述降压药物尤其是血管紧张素转化酶抑制剂( )和血管紧张素 受体拮抗 剂(ARB)对透析患者的独立于降压作用以外的RRF保护作用。 76 关键词：残余肾功能；降压药物；血液透析；腹膜透析 2 0 + 0 中图分类号：R972 .4 A 1672-9188 2009 02-0076-06 文献标识码： 文章编号： ( ) 9 V o l . 3 0 Residual renal function of patients undergoing dialysis and its protection N o . 2 XIAO Xing-xian, ZHANG Yi-min (Department of Nephrology, The Second Affi liated Hospital, Sun Yat-san University, Guangzhou 510120, China) Abstract: Residual renal function RRF is an important determinant of mortality and morbidity in patients ( ) undergoing dialysis. This paper reviews the importance of RRF, the measurement of RRF, factors that infl uence RRF in patients with haemodialysis and peritoneal dialysis, and measures to preserve RRF in dialysis patients. Evaluated therapeutic approaches, especi