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新释药系统研究进展--张强(北京大学药学院)北京20110715
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新释药系统研究进展Advances in drug delivery systems
张 强
北京大学药学院
Topical
epicutaneous (application onto the skin), e.g. allergy testing, typical local anesthesia
inhalational, e.g. asthma medications
enema, e.g. contrast media for imaging of the bowel
eye drops (onto the conjunctiva), e.g. antibiotics for conjunctivitis
ear drops - such as antibiotics and corticosteroids for otitis externa
intranasal route (into the nose), e.g. decongestant nasal sprays. Nasal administration can also be used for systemic effect.
vaginal, e.g. topical estrogens, antibacterials
Enteral
Enteral is any form of administration that involves any part of the gastrointestinal tract:
by mouth (orally), many drugs as tablets, capsules, or drops
by gastric feeding tube, duodenal feeding tube, or gastrostomy, many drugs and enteral nutrition
rectally, various drugs in suppository or enema form
Parenteral by injection or infusion
intravenous (into a vein), e.g. many drugs, total parenteral nutrition
intraarterial (into an artery), e.g. vasodilator drugs in the treatment of vasospasm and thrombolytic drugs for treatment of embolism
intramuscular (into a muscle), e.g. many vaccines, antibiotics, and long-term psychoactive agents
intracardiac (into the heart), e.g. adrenaline during cardiopulmonary resuscitation (no longer commonly performed)
subcutaneous (under the skin), e.g. insulin
intraosseous infusion (into the bone marrow) is, in effect, an indirect intravenous access because the bone marrow drains directly into the venous system. This route is occasionally used for drugs and fluids in emergency medicine and paediatrics when intravenous access is difficult.
intradermal, (into the skin itself) is used for some allergens, and also for tattoos
intrathecal (into the spinal canal) is most commonly used for spinal anesthesia and chemotherapy
intraperitoneal, (infusion or injection into the peritoneum) e.g. peritoneal dialysis
Intravesical infusion is infusion into the urinary b
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