“US Surgeon General’s Family History Initiative”.pptVIP

THE U.S. SURGEON GENERAL’S FAMILY HISTORYINITIATIVE Why Family History? Almost every disease is due to interactions of multiple inherited (“genetic”) factors and non-genetic (“environmental”) factors. 9 of the 10 Leading Causes of Death Have Genetic Components 1. Heart disease (28.9% of U.S. deaths in ‘01) 2. Cancer (22.9%) 3. Cerebrovascular diseases (6.8%) 4. Chronic lower respiratory dis. (5.1%) 5. Injury (4.0%) 6. Diabetes (2.9%) 7. Pneumonia/Influenza (2.6%) 8. Alzheimer disease (2.2%) 9. Kidney disease (1.6%) 10. Septicemia (1.3%) Indeed, ALL Diseases Have a Genetic Component In causation In how each individual responds physiologically to the disease In how each individual reacts to drugs used to treat them GENES + ENVIRONMENT =HEALTH AND DISEASE Family History ChangesDiagnosis of Many Diseases It is the key to presymptomatic diagnosis If someone is sick, it informs the differential diagnosis – what diagnoses to consider It guides testing to nail down the diagnosis Family History Changes Population Screening Guidelines Visual Impairment Hearing Impairment Thyroid Disease Thromboembolism Hypertension Diabetes Coronary Artery Disease Dyslipidemia Breast Cancer Colon Cancer Prostate Cancer Liver Cancer Hip Dysplasia Iron Def Anemia Osteoporosis Cardiomyopathy Family History ChangesManagement of Common Disease Coronary Heart Disease Hypertension Heart Failure Emphysema COPD Syncope Pancreatitis Diabetes Thromboembolism Thyroid Cancer Breast Cancer Colon Cancer Urticaria Developmental Delay Pancreatitis But Do People Care About Family History? In 2004, Research!America and Parade conducted a nationwide survey of 1,000 individuals: 65% have found health information on the Internet to be very or somewhat helpful But, 96% thought, in thinking of their own health, that knowledge of family health history was very or somewhat important But Do People Care About Family History? In a CDC survey of 4,000+ individuals: 97% thought that knowledge of family heal