两种不同类型弱视儿童治疗前后多焦视网膜电图变化对比.doc

两种不同类型弱视儿童治疗前后多焦视网膜电图变化对比 　　【摘要】 目的：用多焦视网膜电图方法对两种弱视眼治疗前后的视网膜功能分别进行对比分析，探讨两种弱视眼视网膜功能的状况，为临床弱视治疗效果提供客观敏感的检查指标。方法：选择本院确诊为斜视性弱视30例（30眼），屈光参差性弱视30例（30眼），使用多焦视网膜电图（multifocal ERG，mfERG）方法检测60例弱视儿童。对治疗前后、两种不同弱视的mfERG峰值振幅密度分别进行比较。结果：斜视性弱视治疗前后mfERG第一环与第二环峰值振幅密度差异有统计学意义（P0.05）。两种不同类型的斜视治疗前后各环峰值振幅密度差异均无统计学意义（P0.05）。结论：斜视性弱视与屈光参差性弱视儿童在治疗前后，黄斑区视网膜功能存在明显的特征性改变；两种不同类型的弱视眼黄斑区视网膜功能的异常未见明显差异 【关键词】 弱视； 多焦视网膜电图； 电生理； 视网膜 Changes Multifocal ERG before and after Treatment of Two Different Types Amblyopia of Children/ZHU Jun-ying，FU Zheng，WANG Qian，et al.//Medical Innovation of China，2016，13（35）：109-112 【Abstract】 Objective：To compare the two amblyopic eye retinal function before and after treatment were compared separately by the multifocal ERG method， to investigate the function of two amblyopic eye retina，and to provide an objective examination sensitive indicators for clinical amblyopia treatment.Method：A total of 30 cases of strabismus amblyopia（30 eyes） and anisometropia amblyopia 30 cases（30 eyes） were diagnosed in our hospital，our hospital diagnosed the use of multifocal ERG detected 60 cases of children with amblyopia. Before and after treatment of amblyopia， mfERG peak amplitude density of two different amblyopia were compared.Result：Strabismus amblyopia mfERG first peak amplitude of the second ring density differences were statistically significant before and after treatment（P0.05）.Anisometropia amblyopia mfERG fifth peak amplitude of the density difference between the second ring was statistically significant（P0.05）.The peak amplitude of each ring density difference between two different types of strabismus before and after treatment were not statistically significant（P0.05）.Conclusion：There is a distinct characteristic changes in macular function before and after treatment in children with anisometropia amblyopia and strabismus amblyopia.Amblyopic eye macular function has no significant difference in two different types of abnormalities. 【Key words】 Amblyopia； Mult