无抽搐电休克治疗难治性精神分裂症临床探究.docVIP

无抽搐电休克治疗难治性精神分裂症临床探究 　　【摘要】 目的：探?无抽搐电休克对难治性精神分裂症的治疗效果。方法：选取86例难治性精神分裂症患者作为研究对象，随机进行分组，对照组采取氯氮平治疗，研究组在氯氮平治疗的基础上，采取无抽搐电休克治疗，对比两组治疗前后的阳性和阴性症状量表评分表（PANSS）评分，根据副反应量表（TESS）评分、改良韦氏记忆量表（WMS）评分，综合评价无抽搐电休克对难治性精神分裂症的治疗效果及安全性。结果：治疗后，研究组阳性症状评分、阴性症状评分、一般精神病理症状评分、PANSS总分均显著低于治疗前，且与对照组对比，差异均有统计学意义（P0.05）；在研究组患者的WMS评分中，治疗结束后14 d时，研究组患者的再认、图片、联想、背数记忆评分均显著低于治疗前（P0.05）。结论：无抽搐电休克对难治性精神分裂症的治疗效果确切，可显著改善患者的临床症状，治疗副反应发生少，对患者的记忆功能影响具有暂时性、可逆性，安全性较高 【关键词】 难治性精神分裂症； 无抽搐电休克； 治疗效果 doi：10.14033/j.cnki.cfmr.2016.32.002 文献标识码 A 文章编号 1674-6805（2016）32-0003-03 Clinical Study of Modified Electric Shock Therapy in the Treatment of Refractory Schizophrenia/ZHANG Yu-mao，GUO Yu-hua，HUANG He，et al.//Chinese and Foreign Medical Research，2016，14（32）：3-5 【Abstract】 Objective：To explore the therapeutic effect of modified electric shock in the treatment of refractory schizophrenia.Method：A total of 86 patients with refractory schizophrenia patients were selected as the research object，they were randomly divided into two groups，patients in the control group were treated by Clozapine，on the basis of the control group，the study group took modified electroconvulsive therapy， between the two groups before and after treatment，the positive and negative symptom scale score（PANSS） score were compared，the therapeutic effects and safety were comprehensive evaluated according to the amount of side reaction table（TESS） score and modified Wechsler Memory Scale（WMS） score.Result：After the treatment， the positive symptoms，negative symptoms，general psychopathology symptoms scores of PANSS total score in the study group were significantly lower than before treatment，and with the control group，with significant difference（P0.05）.In the study group of patients with WMS scores，the end of treatment after 14 days，patients with recognition，pictures，lenovo，back number memory scores were significantly lower than before treatment（P0.05）.Conclusion：Modified electroconvulsive refractory spirit of split exact treatment of disease，c