2011-04创伤致死三联征.pptVIP

严重创伤后凝血功能障碍的早期预警 长时转运 输血15u ISS 25~35 pH 7.1~7.2 低血压 70分钟, SBp 70mmHg 体温 34~35 ℃ BE ≤ -15 “The Triad of Death”预防及治疗策略 Strategies to correct coagulopathy Reverse hypothermia and maintain an effective circulating blood volume and oxygenation Preferably use whole blood and/or the freshest available Give FFP（鲜冻血浆） to replace coagulation factors (10—15 ml/kg approx. 2 units will achieve 30% factor activity in adults) Give platelets Give cryoprecipitate(冷凝蛋白沉淀物） Strategies to correct coagulopathy Give calcium (10 mmol) to reverse hypocalacaemia Consider the use of adjuncts to promote coag