不可逆转的失明之后眼周的自体富含血小板等离子皮肤再生疗法.docxVIP

CASE REPORTS病理报告Irreversible Blindness Following PeriocularAutologous Platelet-Rich Plasma Skin Rejuvenation Treatment 不可逆转的失明之后眼周的自体富含血小板等离子皮肤再生疗法KrishnapriyaKalyam, M.D., Shaheen C. Kavoussi, M.D., Michael Ehrlich, M.D., Christopher C. Teng, M.D., NishaChadha, M.D., Sarah Khodadadeh, M.D., andJi Liu, M.D. KrishnapriyaKalyam,医学博士卡佛西,夏新,医学博士,迈克尔?埃利希。克里斯托弗·c·腾医学博士,尼莎查达医学博士莎拉Khodadadeh,医学博士,和刘霁,医学博士Abstract: 摘要：A 49-year-old woman developed acute visual loss in the right eye following bilateral cosmetic platelet-rich plasma injections to rhytids in the glabellar region. External exam showed skin necrosis in the region over the right rhytids and restricted right ocular motility. Dilated fundus exam was significant for ophthalmic artery occlusion. Imaging revealed right eye extraocular muscle ischemia and optic nerve infarction, along with right frontal, parietal, and occipital lobe infarction. Work-up for thromboembolic and vascular etiologies were negative. To our knowledge, this is the first case reported of extensive ischemia following autologous platelet-rich plasma therapy. 49岁的妇女发展敏锐的视力丧失在双边整容后的右眼富含血小板等离子体注入rhytids在眉间的地区。外部检查在该地区显示皮肤坏死rhytids和限制对眼部的能动性。扩张眼底检查是重要的眼动脉阻塞。成像显示右眼眼外肌缺血和视神经梗塞,右额叶,顶叶,和枕叶梗死。血栓栓塞的诊断检查和血管性病因是负的。据我们所知,这是第一例报道广泛的缺血自体富含血小板血浆治疗。CASE REPORT病理报告The case reported here is in compliance with the Health Insurance Portability and Accountability Act (HIPAA) regulation. An otherwise healthy 49-year-old woman presented to the Yale Eye Center complaining of acute loss of vision in the right eye associated with severe nausea and eye pain. One day prior, the patient underwent an autologous platelet-rich plasma (APRP) injection procedure by an unlicensed practitioner to reduce wrinkles in the glabellar region bilaterally. She reported that blood was taken from her antecubital region by venous puncture and centrifuged to obtain concentrated autologous plasma. Bilateral forehead rhytids injections were performed. The patient was unaware the details of the plas